Metabolic health is a connected story: diet, movement, sleep and stress. BERBELLE is one simple, science-led part of it. Two clearly identified botanicals, two capsules a day.
60 servings · 2-month supply
3 bottles · 6-month supply · £19.99 per bottle
5 bottles · 10-month supply · £17.99 per bottle
A focused botanical food supplement combining 1,200mg Berberine HCl and 100mg Ceylon Cinnamon (Cinnamomum verum) per serving, taken as 2 vegetarian capsules daily.
Take 2 capsules daily with a meal and water. Each bottle has 120 vegetarian capsules: 60 servings, or 2 months. Do not exceed the recommended daily dose.
We separate what researchers have studied from what our product can claim. Berberine and cinnamon have been studied as ingredients in human trials, but the finished BERBELLE formula has not been tested in its own clinical trial. See Our Science for the full summary.
Most everyday cinnamon is cassia, which contains considerably more coumarin. Ceylon ("true cinnamon") is generally much lower in coumarin.
The most commonly reported effects of berberine are digestive, such as nausea, bloating, constipation or diarrhoea. Berberine can interact with medicines. Speak to a healthcare professional before use if you take medication (especially for blood sugar) or have a medical condition. Not suitable during pregnancy or breastfeeding.
You're charged and sent a new bottle every 2 months at 15% off. There's no minimum term: pause, skip or cancel anytime from your account before the next billing date.
Metabolic health is shaped by more than one thing. Diet, movement, sleep and stress interact with how your body manages energy, responds to insulin and stores fat, often quietly and over years.
There's no single culprit, and no single fix. But the right foundations, plus a focused daily routine, can be part of the picture.
Diet · movement · sleep · stress
How the body manages energy can change over time
Cells become less responsive to insulin
A pattern worth understanding, not a diagnosis
BERBELLE is a focused botanical food supplement designed to complement, not replace, a balanced diet, regular movement, good sleep and sensible stress management.
2 capsules daily · 120 vegetarian capsules · 60 servings
We separate what researchers have studied from what our finished product can claim. These figures come from published ingredient research, not a trial of BERBELLE.
Randomised trials in a 2023 berberine meta-analysis
Participants across those included trials
Daily berberine range most used in trials. BERBELLE provides 1.2g.
Length of a 2025 RCT using 1,200mg berberine with cinnamon
Most published berberine studies ran for 8–12 weeks or longer. Consistency matters more than intensity.
2 capsules with a meal and a glass of water.
Taking it with food helps your stomach settle into the routine.
Pair BERBELLE with the foundations: nutrition, movement, sleep and stress.
3 bottles = 6 months. That's why Buy 2, Get 1 Free is our most popular option.
| BERBELLE | Many berberine products | |
|---|---|---|
| Form clearly stated (Berberine HCl) | ✓ | Often unclear |
| 1,200mg per serving, fully disclosed | ✓ | Varies |
| Ceylon (low-coumarin) cinnamon | ✓ | Cassia or none |
| Halal & GMP certified, vegetarian capsules | ✓ | Not always |
| Research published honestly, including limits | ✓ | ✕ |
Buy 2, Get 1 Free: 6 months of BERBELLE for £59.98.
BERBELLE is a food supplement and should not replace a varied, balanced diet and healthy lifestyle.
Metabolic health is shaped by more than one thing. Diet, movement, sleep and stress can interact with insulin regulation, body-fat distribution and inflammatory processes over time.
Rather than blaming one hormone or one food, it helps to look at the wider picture.
Diet · movement · sleep · stress
How the body manages energy can change over time
Cells become less responsive to insulin
The body may produce more insulin to maintain glucose control
A pattern worth understanding, not a diagnosis from a webpage
Educational content only. Metabolic health is multifactorial and individual. This diagram intentionally simplifies complex physiology.
Metabolic syndrome is the name given to a cluster of risk factors that can occur together. It is not simply "high insulin". Insulin resistance, abdominal adiposity, blood pressure, blood lipids and glucose regulation can all form part of the wider clinical picture.
The important idea: these factors can be interconnected, and lifestyle foundations matter.
How effectively the body manages circulating glucose.
How cells respond to the hormone insulin.
Where fat is stored can matter as well as how much.
Blood pressure and lipid markers are part of the broader picture.
Cortisol is a normal hormone involved in the body's stress response. Short-term rises are part of healthy physiology. Problems are more nuanced than simply having "high cortisol". Chronic stress, disrupted sleep and behavioural changes can interact with metabolic health.
Physical or psychological demands
Including the HPA axis
Normal regulation can be affected
Factors that can influence metabolic health
Cortisol is essential to health. This section does not suggest that cortisol is inherently harmful or that BERBELLE changes cortisol levels.
Visceral fat is stored around internal organs and is biologically different from the fat stored directly under the skin. Research links excess visceral adiposity with cardiometabolic risk and chronic low-grade inflammatory signalling.
But there is no single "culprit". Visceral fat, insulin resistance, inflammatory processes, sleep, diet, activity and stress can all influence one another.
No capsule replaces the fundamentals. A varied, balanced diet, regular movement, sufficient sleep and sensible stress management are the foundation.
Build meals around minimally processed foods, fibre and appropriate portions.
Regular activity and resistance exercise support overall health.
Protect a consistent sleep routine and adequate recovery.
Create repeatable ways to recover from daily demands.
BERBELLE is a focused botanical food supplement designed to complement, not replace, your everyday routine.
2 capsules daily · 120 vegetarian capsules · 60 servings
Halal Certified • GMP Certified • Vegetarian Capsules
We separate what researchers have studied from what our finished product can claim.
Randomised trials in a published berberine meta-analysis
Participants across those included trials
One of several pathways discussed in mechanistic berberine research
Human studies and systematic reviews have investigated berberine across glucose, insulin-related and lipid markers in studied populations. Mechanistic research also discusses AMPK, a cellular energy-sensing pathway involved in glucose and lipid metabolism.
A biological mechanism does not prove a specific health outcome from BERBELLE.
Cinnamon has been investigated in human trials, but studies vary in species, preparation and dose. Ceylon cinnamon is generally much lower in coumarin than cassia cinnamon.
Research using other cinnamon preparations or larger doses should not automatically be attributed to BERBELLE's 100mg serving.
1,200mg Berberine HCl + 100mg Ceylon Cinnamon per serving.
£29.99 one bottle · 60 servings
Or Buy 2, Get 1 Free: 6 months for £59.98
BERBELLE combines Berberine HCl and Ceylon Cinnamon in one straightforward formula: 1,200mg Berberine HCl + 100mg Ceylon Cinnamon per serving, taken as 2 vegetarian capsules daily.
Berberine HCl (berberine hydrochloride) is a defined salt form of berberine, commonly used in supplements and extensively represented in published research. Simply seeing the word "berberine" on a product doesn't tell you the exact form being supplied. BERBELLE clearly identifies its form.
Much of the everyday cinnamon sold commercially is cassia. BERBELLE uses Ceylon Cinnamon (Cinnamomum verum), known as "true cinnamon", which is generally much lower in coumarin.
60 servings. Each serving is 2 capsules, and each bottle contains 120 vegetarian capsules.
Speak with an appropriate healthcare professional before use. Berberine can interact with medicines and may not be appropriate for everyone.
A transparent summary of published human studies on berberine and cinnamon, covering what the research shows and where the evidence is still developing.
Important scope. This page summarises published research on the ingredients. It is not proof that BERBELLE prevents, treats or cures any disease. The exact formula (1,200mg berberine + 100mg Ceylon cinnamon) has not yet been tested in a published randomised clinical trial. Evidence reviewed through August 2026.
Within the common clinical range. A 2024 meta-analysis found 0.9–1.5g/day was the most common dose in trials.
Lower than most cinnamon trials, many of which use gram-level doses. We don't present it as independently dose-proven. We chose Ceylon for its low coumarin content.
| Area studied | Evidence | What research shows | Key limitation |
|---|---|---|---|
| Insulin-resistance markers | Supportive | RCT meta-analyses report reductions in HOMA-IR and fasting insulin with berberine. | Studied in metabolic populations. |
| Fasting glucose / HbA1c | Supportive | Modest reductions. A 2025 RCT (1,200mg berberine + 600mg cinnamon) improved both vs placebo. | That trial used 600mg cinnamon, not 100mg. |
| Blood lipids | Supportive | Reductions in LDL-C and/or triglycerides in some metabolic populations. | Varies by population and study. |
| Liver-related markers | Promising | NAFLD meta-analyses report improved liver enzymes, HOMA-IR, BMI and lipids. | Clinical populations. Trials are inconsistent. |
| Body weight | Limited–moderate | ~0.88kg average reduction in a recent meta-analysis. Earlier reviews are mixed. | 2026 RCT: no visceral-fat reduction at 1g/day. |
| Ceylon cinnamon 100mg | Insufficient dose data | Cinnamon research is mixed and often uses ~0.12–6g/day. | Not proven at 100mg. |
Including results that found no effect, because an honest picture matters.
2023 meta-analysis of 20 RCTs (n=1,761): fasting insulin −2.36 mU/L and HOMA-IR −0.85 vs placebo on average.
PMID 375987531,200mg berberine + 600mg cinnamon for 12 weeks lowered fasting blood sugar, HbA1c and LDL-C vs placebo in type 2 diabetes. No difference in other measures.
Mansour et al., Eur J Nutr 2025 · PMID 399987032025 meta-analysis of 23 RCTs: −0.88kg weight, −0.48 BMI and ~−1.32cm waist vs control, with study-quality limitations.
PMID 41310257A 2026 RCT (337 adults): 1g/day berberine for 6 months did not reduce visceral or liver fat vs placebo. LDL-C, apoB and hs-CRP improved modestly.
PMID 415438542024 NAFLD meta-analysis (10 RCTs, 811 people): improvements in ALT, AST, GGT, lipids, HOMA-IR and BMI. Mild digestive side effects reported.
PMID 384297942023 meta-analysis of 24 RCTs: improved fasting blood sugar, HOMA-IR and HbA1c, but not serum insulin. Doses varied widely.
PMID 37818728Laboratory research discusses berberine and AMPK, a cellular energy-sensing pathway, along with liver glucose production, lipid metabolism and the gut microbiota. Cinnamon research looks at glucose transport and insulin signalling.
A biological mechanism does not prove a specific health outcome from BERBELLE.
Seeing the word "berberine" on a label doesn't tell you the exact form being supplied. BERBELLE names the form, the species and the dose. No proprietary blends.
Berberine is a naturally occurring plant compound found in several plants. Berberine HCl (berberine hydrochloride) is a defined salt form commonly used in supplements and extensively represented in published research.
Not all cinnamon is the same. Much of the cinnamon sold commercially is cassia. BERBELLE uses Ceylon cinnamon, known as "true cinnamon", which is generally much lower in coumarin.
Other ingredients: vegetarian capsule shell. [add exact wording from the label]
Take 2 capsules daily with food. Do not exceed the recommended dose. Not suitable during pregnancy or breastfeeding. Speak to a healthcare professional if you take medication.